Medullary thyroid carcinoma


Medullary thyroid carcinoma is the third supreme common type of thyroid cancer. This cancer can be connected to other endocrine tumors.  Medullary thyroid carcinoma can spread to distant organs and also to the liver, bone, brain and the adrenal medulla. It generally begins from the upper central lobe of the thyroid. Thecancer originates from the parafollicular cells of the thyroid. In this setting, the peak beginning of medullary thyroid cancer is between 40 and 60 years old. The ratio of females to males is 3:2.

Multiple endocrine neoplasia syndromes are a collection of endocrine disorders that take place together in the same patient and is normally seen in families as they are innate. This syndrome is caused as a result of a defectin a gene that aidsin monitoring the normal growth of endocrine tissues.

This inborn syndrome is passed on to all children who get the gene, which supposedly, would be 50% of all offspring of a person with this defective gene. Due to this, males and females are affected equally.  The peak occurrence of medullary carcinoma in these patients was in the 30s.

Inherited medullary carcinoma without associated endocrinopathies

This form of medullary carcinoma is the least destructive. Like the other kinds of thyroid cancers, the peak occurrence is between 40 and 50 years old.


Some symptoms that may appear to consist of roughness that has no known cause and does not go away, difficulty in breathing or short breaths, problem in swallowing or an uncommon sensation observed when swallowing, lump seen at the base of the neck and an unusuallylarge lymph node that fails to instinctively contract over a few weeks’ time.


  The treatment possibilities and suggestions depend on several factors consisting of

  • The category and phase of cancer.
  • The probable side effects.
  • Preferences of the patient.
  • The overall health of the patients.

The primary treatment is to surgically remove the thyroid. If there is an indication of involved lymph nodes in the neck, these are removed as well. Depending on the size of the nodule common surgical operations that contain are lobectomy. This type of surgery removes the gland lobe with the carcinogenic nodule. The second surgery is a subtotal thyroidectomy, this surgery is done toeliminatethe thyroid gland excluding a small part. The third surgery is total thyroidectomy. This surgery eradicates the complete thyroid gland.

Treatment Complications


After the surgery, which includes removing the lymph nodes along one side of the neck, the area becomes numb for some time. Oftenboth the left and right side neck lymph nodes have cancer. In this case, then altered fundamental neck dissections on one side and then the other may be done about 2 months apart. By doing the lymph node dissection on both the sides could result in an unnecessary swelling of the head and face in case time is not given between operations.


Postoperative Care

For some people who are suffering from cancer, cancer does not get cured completely. These people may get treatments regularly, such as using chemical agents to treat disease;radiotherapyor other therapies help keep cancer in check. If you have completed treatment, the doctors will still want to watch you thoroughly. It is very important to go to all follow-up appointments. During these visits, the doctors will ask about the symptoms, inspect and might order blood tests or imaging tests such as ultrasounds. Follow-up is necessary to check for cancer recurrence or spread.