Follicular Thyroid Carcinoma


FollicularThyroidCarcinomaCancer is the second most common type of Thyroid Cancer. However,Papillary Thyroid Cancer is the most common type of Thyroid Cancer.Thyroid neoplasms arising from different follicular cells,i.e. adenoma, carcinoma and follicular/papillary carcinoma shows a broad range of overlapping clinical and cytologic features.For only this reason, a surgical procedure to remove a large or a whole portion of the thyroid gland may be required to obtain sufficient tissue for a definite diagnosis of follicular tthyroid Carcinoma. Pathological examination shows that capsular or vascular invasion may be required for this determination.


Papillary and FollicularThyroid Carcinoma are considered as the differentiated form of Thyroid cancers, together they make around 95% of Thyroid Cancer Cases.

Thyroid Cancer is found more often in patients having a history of low or highdose of external irradiation to the thyroid or cervical area. Patients who are havingThyroid Cancer and developed the radiation in the head and neck area have more chance of this extensive disease.Around6% of patients with Thyroid cancer have metastases beyond the mediastinal or cervical area in initial stage, as is3-4% of patients with Papillary Thyroid Cancer and 15% of patients with Follicular Thyroid Carcinoma (FTC). Few10-15% of patients with Thyroid Cancer die of this disease.


Some of the experts believe the factthat ifthe tumors are smaller in size and not affectingother tissues, thenonlyby removing the lobe of the thyroid that surrounds the tumor and the small central portion called the isthmus provides a good cure byremoving the entire thyroid.The opposite side of the above controversy is AbsoluteThyroidectomy which is a more aggressive surgery option.

Follicular Thyroid Carcinomas which are isolated,well circumscribed, minimally invasiveand less than 2 cm in a patient younger than 45 years old can be treated with isthmusthectomy and hemi-thyroidectomy. The rest shouldbe treated with absolute thyroidectomy and the removal of enlarged lymph nodes in the lateral or central neck areas.

Here are the following Follicular Thyroid Carcinoma(FTC)treatments which may be organized in the following way:

Radioactive Iodine Therapy for Follicular Thyroid Carcinoma

oThyroid cells have a unique property that they can absorb Iodine inside their body as well. Iodine cells use thyroid cells to make Thyroid Hormone. No other cell except Thyroid cell can concentrate orabsorb iodine. Follicular Carcinoma Cells absorb Iodine and therefore are targeted by giving I-131, the toxic isotope.Not everyone with Follicular Thyroid Cancer needs Radioactive Therapy,but those patients with large tumors, spreads to lymph nodes or other areas,tumors that invade blood vessels within the thyroid, tumors that appear aggressive microscopically and older patients may benefit from this therapy.

Thyroid Hormone Replacement for Follicular Thyroid Carcinoma

oDespite ofa patient havingthe entire thyroid gland removed with a total thyroidectomy orthe isthmus and thyroid lobe removed, or, many experts agreeing to the patients being placed on thyroid hormone for remaining of their lives. Thisis done to replace the missing hormone in patients whose thyroid gland has been removed and to suppress the further growth of the gland in the patients who have some tissue left in the neck.This results in a decrease in TSH level and a lower impetus for the remaining cancer cells to grow.


Treatments for Follicular Thyroid Carcinoma depends upon the followingfactors :

  • When the thyroid is detected.
  • Thyroidremaining after surgery.
  • To Check if the thyroid has a major spread.
  • The level of the radioactive iodine may harm during the Therapy, so care must be taken.
  • Proper diagnosis of the FTC must be done.

Post operative care

Followingpostoperativecarehas to be taken forFolllicular Thyroid Carcinoma:

  • Post Treatment patient shouldbe overseen by adoctor who specializes in this field and regularcheck ups from the doctors is needed.
  • Patients should be administered under the proper care of Expert Team post surgery or therapies.
  • Proper Monitoringof the symptoms whichdepicts a comeback of the cancer and consult the doctor/s atleast once a month.